This is good guidance from the JPII institute. There are serious concerns that at least some vaccines for coronaviruses can cause increased severity of disease in response to exposure to the virus after immunization. So, before consenting to a trial ask:
1. Were animal studies conducted with the vaccine?
2. How many different animal models were tested with the vaccine?
3. Was there any evidence of toxicity with the vaccine?
4. Were the animals that received the vaccines subsequently challenged with the wild-type virus and what was the outcome of those studies?
I would only add that we should also be asking whether cell lines derived from aborted children were used in the development of a vaccine as well.